Research Programs

SPG4 Genetic Research Study

Researchers at Baylor College of Medicine are enrolling subjects in a genetic research study of type 4 autosomal dominant spastic paraplegia (SPG4). They are studying the way that different types of gene mutations lead to differences in clinical symptoms among SPG4 patients.

If you or your family member has been diagnosed with a "deletion" or "duplication" mutation in the SPG4 disease gene (this gene is also called SPAST), you will likely qualify to participate.

If you are interested in participating or would like more information, please contact Philip Boone, MD PhD, at pmboone@bcm.edu or at (713)798-6873.

HSP Genetic Study

There is a HSP genetic study currently underway at the University of Miami. If you are interested in participating or finding out more information, please contact Fiorella at mihgHSP@med.miami.edu.

The Miami Institute for Human Genomics Genetic is looking for INDIVIDUALS and their FAMILIES who would like to participate in Hereditary Spastic Paraplegia (HSP) research. The purpose of the research study is to identify genetic factors that contribute to Hereditary Spastic Paraplegia (HSP). Any individual with a Hereditary or Familial Spastic Paraplegia (HSP/FSP) diagnosis and, if willing, selected family members of the individual; can participate. Participation is free of charge. Travel to the University of Miami is not required. Trained staff from our team will perform a family and medical history interview, focused neurological exam, review of your medical records related to HSP, and a small blood sample (about 2 tablespoons). We maintain the highest standards of confidentiality for all families.

If you are interested in participating, please contact the HSP study coordinators at 1 (877) 686-6444 (toll free). You may also email us at mihgHSP@med.miami.edu. Please visit our web site at www.mihg.org for more information.